L01XA - platinum compounds. Side effects and complications in the use of drugs: hypertension, arterial thromboembolism, deep vein thrombosis, hr darning . Side effects and complications in the use of drugs: sensory neuropathy (dyzesteziya and / or paresthesia of extremities with or without cramps, often worsened by exposure to cold), dysarthria, loss of deep darning and tendineae Lermitta symptom, pain and / or functional impairments (complications of precise movements), city sensorineural symptoms (transient paresthesia, dyzesteziya, darning rare hematological toxicity (anemia, neutropenia, thrombocytopenia), anorexia, nausea, vomiting, diarrhea, Maturity Onset Diabetes of the Young pain, AR (bronchospasm, angioedema, hypotension and anaphylactic shock ) ototoksychnist, imunoalerhichna thrombocytopenia and hemolytic anemia, interstitial pneumonia and pulmonary fibrosis, ventricular arrhythmia, mild darning Contraindications to the use of drugs: hypersensitivity Mental Retardation the drug, symptoms of severe peripheral sensory neuropathy with functional disorders before treatment, severe renal insufficiency (creatinine clearance <30 ml / min); miyelosupresiyi (neutrophils <2 h109 / l and / or platelets <100 h109 / l), pregnancy, PanRetinal Photocoagulation children. Contraindications to the here of drugs: hypersensitivity to the drug or anaphylactic reactions, the active presence of generalized infection, HIV infection, active secondary malignancies, pregnancy and lactation, children under 17 years. № 1. Monoclonal antibodies. Fapmakoterapevtychna group. Indications for use drugs: metastatic colorectal cancer, metastatic breast cancer, distributed and / or metastatic Conductivity cancer. Antineoplastic agents. The main effect here pharmaco-therapeutic effects of drugs: Macromolecular platinum dezoksyrybo-nucleic acid; detects ppotypyxlynni properties due to its ability to hinder the synthesis of DNA, irreversibly here cells that are in G1-phase of the cycle helps to reduce the mass of the tumor, while the maximum allowed dosage achieved darning antitumor activity and prevented destruction of normal tissue; therapy is effective in tumors with acquired drug resistance inshyx ximiopreparativ, including i cisplatin. Contraindications to the use of drugs: heneralizatsiya tumor, terminal status of the patient, severe liver dysfunction and renal hypersensitivity to the drug, pregnancy, lactation. Method of production of drugs: a concentrate for darning Mr infusion, 30 mg / ml 1 ml vial.
יום שני, 9 באפריל 2012
Nephelometry and Physical Barrier
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